OncoFOLLOW : Personalized liquid biopsy for patient monitoring

SAMPLE TYPE: Liquid biopsy

MATERIAL: 2 blood samples

First personalized liquid biopsy

Monitor the progression and detect lack of response

OncoFOLLOW is a test based on the analysis of circulating tumor DNA in blood. It is used to monitor the progression of the tumor (burden of the disease) and to detect lack of response or resistance to treatment as soon as it appears.

This assay is customised for each patient, as it analyses up to 15 variants previously identified in the tumour of the patient. In addition, it sequences a fixed panel of 40 genes associated with response/resistance to targeted therapies and immunotherapy, and/or frequently mutated in cancer.

In 2013, OncoDNA became the first company to launch a personalized liquid biopsy test.

SAMPLE TYPE:

Liquid biopsy

RECOMMENDED FOR:

All stage IV solid tumours in adults that have been previously sequenced (with OncoDEEP or any other test sequencing more than 100 genes).

GENES PANEL:

  • 40 genes
  • Up to 15 variants previously identified in the tumour

MATERIAL:

2 blood samples (2x10ml Streck tubes)

Unique Gene Panel For Each Patient

Personalized tool

The gene panel is customised for each patient by selecting a set of patient-specific variants, which were identified in the tumour by a previous sequencing test (with OncoDEEP, or with any other test sequencing more than 100 genes

gene panel ctdna liquid biopsy

A minimally invasive technique

From a simple blood sample, this minimally invasive technique allows to follow the treatment response very closely and identify new targets if the cancer becomes resistant to the current therapy, and it may detect relapse earlier than routine imaging technologies.

Clinical evidence

OncoDNA scientific team regularly publishes studies in peer-reviewed international journals. We have selected for you the key scientific publications that highlight the clinical impact of our OncoFOLLOW test.

Circulating tumor DNA in early response assessment and monitoring of advanced colorectal cancer treated with a multi-kinase inhibitor

Oncotarget 2018

The clinical impact of using complex molecular profiling strategies in routine oncology practice

Oncotarget 2018

EML4-ALK translocation identification in RNA exosomal cargo (ExoALK) in NSCLC patients: a novel role for liquid biopsy

Translational Cancer Research 2019

Other Biomarker Tests

OncoDEEP®

Comprehensive biomarker test to support clinical decisions

OncoDEEP® offers a unique combination of DNA, RNA and protein biomarker tests on solid biopsies. In less than two weeks, OncoDEEP is able to pinpoint the therapeutic vulnerabilities of an advanced, metastatic tumor and to recommend appropriate treatment options. The test screens for genomic alterations (DNA & RNA), genomic signatures (MSI, TMB, HRD) and protein biomarkers of response to targeted therapies, immunotherapies, hormone therapy and chemotherapy.

OncoSELECT

oncoselect liquid biopsy

Smart and cost-effective liquid biopsy panels with selected key genes per tumor type

OncoSELECT is a fast and minimally invasive analysis of circulating tumor DNA from a blood sample. It is the perfect solution to identify therapeutic options for cancer patients not able to have their tumor biopsied or whose biopsy is too old. It can be used as a tool to detect treatment resistance to targeted and hormonal therapies (before first-line to check the heterogeneity of the disease, or during/after treatment to check for acquired resistance mutations), as well as for monitoring cancer progression.

Frequently Asked Questions

Ordering an OncoFOLLOW test is very simple: Just log in to OncoSHARE and select the diagnostic test(s) you are interested in. If you do not have a kit for sample collection, we will send you one.

After sample processing and interpretation by our expert team, a comprehensive report will be available for you on OncoSHARE. In a simple and interactive manner, it will help you with the selection of the most appropriate treatments based on the unique signature of your patient’s tumour. Moreover, you will also be able to share the report with your colleagues.

For information regarding the price of our OncoFOLLOW test in your respective country, please contact our sales team.

Cannot find what you are looking for? Contact us! Our Scientific Support Teams are available to answer all your questions from Monday to Friday.