Clinical and biological interpretation (OncoKDM)
Clear data insight and clinical interpretation
Analysis details and quality control
Accurate and reliable clinical interpretation of genomic data is essential for labs. OncoKDM provides the necessary views to labs to ensure the quality of sequencing data by enabling them to control key values. However, if labs require a deeper insight into molecular data such as hotspots, they can utilize the advanced Mercury platform.
Watch the videoVariants detection
Our comprehensive variant analysis allows labs to discover all relevant variants detected through sequencing, which are categorized as SNV, INDEL, CNV, AMP. Additionally, we classify each variant based on its biological and therapeutic impact, using the TIER classification system that follows the established ACMG/AMP guidelines ensuring labs receive detailed and accurate information about each variant's potential clinical significance.
Watch the videoGenomic signatures
In addition to identifying individual alterations, the OncoDEEP kit also focuses on complex genomic signatures and rearrangements, such as HRD, MSI, and TM. Our process includes scoring and reporting the expression of these signatures into OncoKDM, enabling labs to access a comprehensive overview of their patients' molecular profile. By incorporating these signatures into the analysis, we provide a more complete picture of the tumor's biology ensuring the best clinical interpretation.
Watch the videoDrugs recommendation
OncoKDM treatment recommendation provides a clear overview of the most effective treatment options based on official guidelines and clinical evidence, ensuring that non-responders are spared from unnecessary toxicities and ineffective therapies. We list each drug with its associated biomarkers and approval details, allowing oncologists to make informed decisions about the best treatment for the patients.
Watch the videoClinical Trials
Easily find worldwide, relevant clinical trials that have reached at least Phase 2, based on your patient's specific condition and molecular profile. With our advanced search capabilities, you can quickly identify clinical trials that are most likely to benefit your patients and provide them with the latest treatment options available.
Watch the videoA comprehensive summary
Our comprehensive reporting includes key findings, simplified pathway analysis, and treatment recommendations based on both molecular and clinical evidence. This allows labs to easily understand the implications of the molecular profiling results and make informed decisions about the best course of treatment for the patients.
Watch the video
Extensive QC data visualization
Besides providing labs with QC data on sample quality such as read length and read quality,
OncoKDM also offers genomic information at both the sample and gene levels.
The most advanced technologies coupled with our clinical expertise
users with a solution but also provide them with a real value for their job."
OncoKDM® is technology-agnostic
No matter how comprehensive or focused, commercial or custom your panel is, OncoKDM® embeds a large library of BioIT pipelines enabling a seamless clinical interpretation of the NGS data.
• AmpliSeq for Illumina BRCA Panel
• AmpliSeq for Illumina Cancer Hotspot Panel V2
• AmpliSeq for Illumina Focus Panel
• AmpliSeq for Illumina Comprehensive Cancer Panel
• TruSight Tumor 15
• TruSight Tumor 170
• TruSight Oncology 500
• Solid Tumor Solution
• Human Breast Cancer Panel
• Human Colorectal Cancer Panel
• Human Lung Cancer Panel
• Human Actionable Solid Tumor Panel
• Human BRCA 1 & 2 Plus Panel
ClearSeq Comprehensive Cancer Panel
